Monoclonal antibodies against melanoma-associated antigens and hybrid cell lines producing these antibodies
AssigneeThe Wistar Institute
InventorsJan Thurin, Hilary Koprowski, Meenhard Herlyn, Zenon Steplewski
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Abstract
The present invention is directed to monoclonal antibodies, and hybridomas which produce them, which are reactive with ganglioside antigens GD2 and GD3 and are essentially non-reactive with other ganglioside antigens. The invention further relates to methods of using these antibodies.
Claims5
A continuous hybridoma cell line capable of secreting monoclonal antibodies reactive with ganglioside antigens GD2 and GD3 and is essentially non-reactive with other ganglioside antigens.
A monoclonal antibody reactive with ganglioside atigens GD2 and GD3, wherein said antibody is preferentially reactive with GD2 and is essentially non-reactive with GQ 1b.
Dependencies are inferred from the claim text.