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AssigneeThe Dow Chemical Company
InventorsTimothy S. Stevens, Nile N. Frawley, Daniel J. Swart, William C. Harris, Deborah E. Diedering, Lawrence W. Nicholson, L. David Rothman
Estimating the term…
An analytical chemistry apparatus and method for introducing a reagent into a flowing stream of liquid carrier in order to quantitatively analyze one or more components of a sample added into the carrier. The reagent is permeated across a short section of membrane having relatively large pores. The use of such a membrane: (a) allows the membrane to be protected from physical damage by covering it with a perforate structure; (b) significantly reduces bandspreading across the membrane reagent addition device; (c) reduces the pressure drop across the membrane reagent addition device; and (d) still allows for the permeation of an effective amount of the reagent into the carrier. The reagent is preferably pressurized to minimize leakage of carrier across the membrane and the reagent can be self-pressurized by essentially completely filling the reagent reservoir of the invention with reagent and then hermetically sealing the reservoir.
In a method of reagent addition to an effluent stream in liquid chromatography wherein the stream is under pressure, comprising the steps of contacting the effluent stream with one side of a two sided liquid and reagent permeable membrane, contacting the other side of the membrane with a liquid mobile reagent contained in a chamber, wherein the improvement comprises the step of:
In a method of reagent addition to a carrier stream in flow injection analysis wherein the stream is under pressure, comprising the steps of contacting the carrier stream with one side of a two sided liquid and reagent permeable membrane, contacting the other side of the membrane with a liquid mobile reagent contained in a chamber, wherein the improvement comprises the step of:
Dependencies are inferred from the claim text.