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US 4,833,165 AGranted
Method of inactivating HTLV-III virus in blood
OwnerAllan L. Louderbackinventor
Life of this patent
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Abstract
HTLV-III virus in blood or blood components is inactivated by treatment with about 0.1-5% of phenol, formaldehyde, or mixtures thereof, at a temperature of about 2.degree.-40.degree. C. for at least about 5 minutes.
Claims5
A method of inactivating HTLV-III virus in blood collected for administration to a human being in need of said blood which comprising the steps of:
- separating red blood cells from whole blood contaminated by said virus washing said red blood cells in a saline solution, resuspending said red blood cells in a saline solution;
- treating said red blood cells with an effective amount of from about 0.1% to about 5% by weight of said resuspended red blood cell and saline solution of a chemical agent selected from the group consisting of phenol, formaldehyde and mixtures thereof at a temperature of from about 2.degree. C. to about 40.degree. C. for at least about 5 minutes;
- and thoroughly washing the residual chemical agent from the thus treated red blood cells with a saline solution.
Dependencies are inferred from the claim text.