Pharmaceutical preparation for obtaining a highly viscose hydrogel or suspension
AssigneeAkzo N.V.
InventorsBobby L. S. Kwee, Johannes G. J. Egberink
Life of this patent
Estimating the term…
Abstract
The invention relates to a pharmaceutical preparation for obtaining a highly viscose hydrogel or highly viscose suspension which is suitable to be introduced by means of an injection syringe into body cavities, and which hydrogel or suspension contains at least a drug, a polymer which is insoluble or sparingly soluble in water but has the capability of swelling in water and a watersoluble thickening agent in a relatively low quantity.
Claims6
Pharmaceutical controlled drug release preparation that, when mixed with water, becomes a highly viscose, homogeneously syringeable hydrogel or suspension, said pharmaceutical preparation comprising at least one drug and at least one polymer, said polymer being insoluble or sparingly soluble in water but having the capability of swelling in water, and further comprising a water-soluble thickening agent, said agent being present in an amount sufficient to prevent separation of water from said hydrogel when being subjected to pressure but less than the amount required to significantly increase the viscosity of the total quantity of water required for swelling the polymer to form the hydrogel or suspension.
Dependencies are inferred from the claim text.