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US 4,814,437 AGranted
Method for preparation of sulfated polysaccharides by treating the polysaccharide with a reducing agent before sulfation
AssigneePharmacia Corporation
InventorsAnthony N. de Belder, Leif G. Ahrgren, Tomas Malson
Life of this patent
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Abstract
A new method for preparation of sulfated polysaccharides by means of pyridine-chlorosulfonic acid reagents. The polysaccharide is before sulfation treated with a reducing agent, e.g. sodium borohydride.
Claims12
A method for producing sulfated polysaccharides by reacting the polysaccharide with a pyridine-chlorosulfonic acid reagent, wherein the polysaccharide before the sulfation reaction is treated with an agent which reduces most of the reducing end-groups of the polysaccharides.
Dependencies are inferred from the claim text.