Antihyperlipoproteinemic 5-substituted sulfur-containing benzimidazole derivatives

A compound of Formula (Ic) ##STR7## wherein A is C.sub.2 to C.sub.4 alkyl substituted by hydroxy on the second carbon atom calculated from the sulfur atom;

• and
• R is phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl or phenylsulfinyl;
• or a pharmaceutically acceptable acid addition salt thereof.

A compound of the Formula (Id) ##STR8## wherein E is C.sub.4 to C.sub.6 alkyl substituted by oxo;

• and
• R is C.sub.4 to C.sub.6 alkyl, phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl, or phenylsulfinyl, or a pharmaceutically acceptable acid addition salt thereof.

A compound of the Formula (Ie) ##STR9## wherein B and E are each C.sub.4 to C.sub.6 alkyl substituted by oxo;

• and
• R is C.sub.1 to C.sub.4 alkyl, phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl or phenylsulfinyl;
• or pharmaceutically acceptable acid addition salt thereof.

A compound of the Formula (If) ##STR10## wherein R is phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl, or phenylsulfinyl;

• or a pharmaceutically acceptable acid addition salt thereof.

A compound of the Formula (Ig) ##STR11## wherein A is C.sub.3 to C.sub.4 alkenyl, C.sub.3 to C.sub.4 alkynyl, or 2-oxo-propyl;

• and
• R is C.sub.1 to C.sub.4 alkyl, phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl, or phenylsulfinyl, or a pharmaceutically acceptable acid addition salt thereof.

A compound of the Formula (Ih) ##STR12## wherein R is C.sub.1 to C.sub.4 alkyl, phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl, or phenylsulfinyl, or a pharmaceutically acceptable acid addition salt thereof.

A compound of Formula (Il) ##STR14## wherein one R is phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl or phenylsulfinyl, and the other R is hydrogen;

• n is 2 or 3;
• or a pharmaceutically acceptable acid addition salt thereof.

A compound of the Formula (Im) ##STR15## wherein B and E stand independently of each other for hydrogen or alkyl having 4 to 6 carbon atoms substituted by an oxo or hydroxyimino group in the .gamma.-position, but one B and E must be different from hydrogen;

• one R is C.sub.1 to C.sub.4 alkyl, phenyl-(C.sub.1 to C.sub.4 alkyl), benzoyl, or phenylsulfinyl, and the other R is hydrogen, or a pharmaceutically acceptable acid addition salt thereof.