Apparatus and method for admixture blood warming
AssigneeMinnesota Mining and Manufacturing Company
InventorEthan B. Wilson
Life of this patent
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Abstract
Rapid mechanical admixing of blood products at a storage temperature of 4.degree. C. with a saline solution in a temperature range of 50.degree.-70.degree. C. results in a mixture temperature sufficient to prevent hypothermia upon transfusion, which temperature rise per volume of the blood products is at a rate commensurate with the flow rate of transfusion equipment while not exceeding the temperature tolerance of the erythrocytes.
Claims38
A method for warming chilled erythrocytes to prevent hypothermia upon transfusion and to prevent hemolysis during warming, said method comprising the steps of:
- (a) admixing a quantity of the erythrocytes with a quantity of saline solution having a temperature in excess of 45.degree. C.;
- and
- (b) conveying the admixture to a point of use.
A method for warming stored blood products having a temperature in the range of 4.degree.-10.degree. C. to a temperature in the range of 32.degree. C. to 39.degree. C. without significant hemolysis, said method comprising the steps of:
- (a) admixing a quantity of the blood products with a quantity of saline solution having a temperature in the range of more than 45.degree. C. to less than 80.degree. C.;
- and
- (b) conveying the admixture to a point of use.
The method as set forth in claim 16 including the step of applying heat to the saline solution within the second container.
Apparatus for warming chilled blood products, said apparatus comprising in combination;
- (a) means for containing a quantity of the chilled blood products;
- (b) a saline solution heated to a temperature in the range of more than 45.degree. C. to less than 80.degree. C.;
- (c) means for housing said saline solution;
- and
- (d) means for admixing the blood products and said saline solution to provide an admixture having a temperature in the range of 32.degree. C. to 39.degree. C.
Apparatus for admixing chilled blood products with a heated saline solution, said apparatus comprising in combination:
- (a) a first container for chilled blood products at a temperature in the range of 4.degree. C. to 10.degree. C.;
- (b) a second container for heated saline solution at a temperature in the range of more than 45.degree. C. to less than 80.degree. C.;
- (c) means for admixing the blood products and the saline solution to provide an admixture having a temperature in the range of 32.degree. C. to 39.degree. C.;
- and
- (d) means for conveying the admixture to a point of use.
Apparatus for rapidly warming chilled and stored erythrocytes from a temperature in the range of 4.degree. C. to 10.degree. C. to a temperature in the range of 32.degree. C. to 39.degree. C. without hemolysis, said apparatus comprising in combination:
- (a) a first container for containing a quantity of the erythrocytes;
- (b) a quantity of heated saline solution at a temperature in the range of 50.degree. C. to less than 80.degree. C.;
- (c) a second container for said saline solution;
- (d) mean for admixing the erythrocytes and said saline solution to effect a heat transfer from said saline solution to the erythrocytes;
- and
- (e) means for conveying the admixture to a point of use.
Dependencies are inferred from the claim text.