Connection device avoiding contamination

A connection device for establishing communication between first and second spaces in a manner that prevents exposure of the spaces to contamination from the environment and vice versa comprising;

• a first unit adapted to communicate with the first space and including a first connector part, a first tubular member of flexible material having an inner sealing surface adapted to seal the first space from the environment by engaging either itself or a surface of a component of the first unit, and an actuating member movable relative to the first connector part between first and second positions;
• a second unit adapted to communicate with the second space and including a second connector part and a second tubular member of flexible material having a sealing surface adapted to seal the second space from the environment by engaging itself or a surface of a component of the second unit;
• the first and second units being engageable such that a portion of the tubular member of at least one of the units is in sealed relation with a portion of a component of the other unit when the member is in the first position;
• and
• the actuating member being adapted upon movement from the first to the second position to invert the first tubular member inside out such that the sealing surface thereof is brought into sealing engagement with a surface of the second connector part and also being adapted to move the sealing surface of the second tubular member into sealing engagement with a surface of a component of the first unit, the inversion of the first tubular member and movement of the second tubular member being such as to displace portions thereof that have been exposed to contamination away from portions of the units that have not been exposed to contamination.