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AssigneeSyn-Tek AB
InventorsFrederick C. Lindberg, Bjorn O. Lund, Britt M. Baga, Mari E. Norgren, Mikael Goransson, Bernt E. Uhlin, Jan S. Normark, David L. Lark
Estimating the term…
An antigen which, as its major immunizing component, comprises a determinant of an adhesin polypeptide or an immunogenically active subsequence thereof or a precursor therefor which is convertible to an immunogenically active form, antibodies against which determinant react with the adhesion polypeptide produced by pathogenic adhesin-forming bacteria which adhere to mammalian tissue, antibodies against such antigen, and DNA expressing, as a principal gene product thereof, such antigen.
An isolated antigen which comprises a pilus component distinct from pilin and substantially free from other components of the pilus, an immunogenically active subsequence of said component or a precursor for said component which is convertible to an immunologically active form, said antigen being one which elicits antibodies inhibiting the adhesion of pathogenic adhesin-forming bacteria to mammalian tissue.
Dependencies are inferred from the claim text.