Process for the reduction of organic compounds using alkali formate salts
AssigneeYissum Research Development Company
InventorsHarold Wiener, Shmuel Vandel, Yoel Sasson
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Abstract
The invention provides a process for reducing substantially water insoluble organic compounds containing reducible groups comprising contacting these compounds with an aqueous solution of a formic acid salt in the presence of a hydrogenation catalyst and in the substantial absence of a phase transfer catalyst.
Claims10
A three phase method for reducing water insoluble organic compounds containing reducible nitro groups or reducible carbon-carbon unsaturated bonds comprising contacting an organic phase containing said water insoluble organic compounds which are to be reduced with an aqueous solution of a potassium formic acid salt which serves as hydrogen donor in the presence of a solid heterogeneous palladium on carbon hydrogenation catalyst and in the absolute absence of a phase transfer catalyst or any surface active agent, wherein the water to formate molar ratio is about 0.5:1 to about 3:1 and the pH is greater than 7.
Dependencies are inferred from the claim text.