Process for the preparation of dimeric aromatic acyl cyanides
AssigneeBayer Aktiengesellschaft
InventorsReinhard Lantzsch, Hermann-Dieter Krall
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Abstract
A process for the preparation of a dimeric aromatic acyl cyanide of the formula ##STR1## in which Ar is optionally substituted phenyl, naphthyl or hetaryl, comprising reaction an acyl halide of the formula Ar--CO--Hal in which Hal is fluorine, chlorine or bromine, with an alkali metal cyanide in a two-phase system comprising water and a water-immiscible or only sparingly water-miscible aliphatic ketone, and in the presence of a phase-transfer catalyst. The products are known intermediates for pesticides.
Claims6
In a process for the preparation of a dimeric aromatic acyl cyanide of the formula ##STR10## in which Ar is phenyl, naphthyl, pyridyl, thiazolyl, pyrimidinyl, thienyl or furyl which is in each case optionally substituted by halogen, alkyl, alkoxy, halogenoalkyl, hydroxyl, halogenoalkoxy, alkylthio, amino, halogenoalkylthio, nitro, cyano, alkylsulphonyl, halogenoalkylsulphonyl, optionally halogen-substituted alkylenedioxy, alkoxyalkyl, halogenoalkoxyalkyl, carboxyl, carbalkoxy or alkoxy-N.dbd.CH--,
- comprising reacting an acyl halide of the formula
- Ar--CO--Hal
- in which
- Hal is fluorine, chlorine or bromine, with an alkali metal cyanide the improvement comprising conducting the reaction in a two-phase system comprising water and a water-immiscible or only sparingly water-miscible aliphatic ketone, and in the presence of a phase-transfer catalyst selected from the group consisting of tetrabutylammonium bromide, triethylbenzylammonium chloride, octyltrimethylammonium chloride, dimethyl-dodecylbenzylammonium chloride, tetramethylammonium chloride and tetrabutylammonium chloride.
Dependencies are inferred from the claim text.