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US 4,791,217 AGranted
Sulphur derivatives of para-methoxycinnamic acid, processes for their production, dermo-pharmaceutical and cosmetic compositions containing them and applications
AssigneeUniversite Louis Pasteur
InventorsDominique D. Robert, Louis L. Jung
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Abstract
Sulphur-containing derivatives of para-methoxycinnamic acid presenting a disulphur bridge and an amino-acid group, preparation process thereof. Applications as active ingredients in dermo-pharmaceutical and cosmetological preparations wherein they exert an activity of solar filters which substantially do not penetrate in the circulatory stream.
Claims11
Sulfurized derivatives of para-methoxycinnamic acid, characterized in that they correspond to the following general formula III:
- ##STR3## in which:
- the cinnamic double bond can exist either in the cis form, or in the trans form
- n is a whole number comprised between 1 and 6
- m is a whole number comprised between 1 and 6 and is preferably equal to 1 or 2
- R.sub.1 is a an OR radical, R being a hydrogen atom or an alkyl or aryl group, R.sub.1 can also be an amino-alkyl or amino-aryl group or have an amino-acid structure giving a peptide linkage
- R.sub.2 represents a hydrogen atom or an alkyl or an aryl group or a group of the formula R'--CO--, R' being an alkyl or aryl group or again R'--CO-- having an amino-acid structure giving a peptide linkage.
3 more elements
Dependencies are inferred from the claim text.