Novel oligosaccharides having pharmacological properties by depolymerization of heparin
AssigneeOpocrin A.P.A.
InventorsPietro Bianchini, Giuseppe Mascellani
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Abstract
Novel oligosaccharide fractions with valuable pharmacological properties are obtained from heparin. They have the same structural characteristics of heparin. The heparin fraction consists of oligosaccharides which contain end groups consisting of iduronic acid 2-sulfate, or glucosamine N, 6-disulfate. Further the oligosaccharides contain and monosaccharide endowed with reducing anomeric carbon, and are constituted by multiples of monosaccharide units.
Claims5
A heparin fraction which is a mixture of oligosaccharides containing an average of 13-17 monosaccharides, said oligosaccharides containing end groups composed of iduronic acid 2-sulfate, or glucosamine N, 6-disulfate, said end-groups monosaccharides containing the reducing anomeric carbon, said oligosaccharides being constituted by multiples of monosaccharide units and having a 4000-5000 molecular weight.
A heparin fraction which exhibits a progressive distribution and which contains even and odd number of saccharide units.
Dependencies are inferred from the claim text.