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US 4,790,988 AGranted
Method and compositions for the treatment of thrombotic episodes
AssigneeUniversity of Florida
InventorsJawahar L. Mehta, Tom G. P. Saldeen
Life of this patent
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Abstract
Fibrinogen degradation product pentapeptide 6A and its variants are used in the treatment of thrombi, in particular myocardial infarcts. In a preferred embodiment pentapeptide 6A and tissue plasminogen activator are administered together to enhance the thrombolytic activity of tissue plasminogen activator.
Claims18
A method comprising administering to an animal having a thrombus a composition comprising a therapeutically effective dose of P6A.
A sterile composition comprising a thrombolytically effective doses of a thrombolytic enzyme and P6A.
Dependencies are inferred from the claim text.