Viral glycoprotein subunit vaccine
AssigneeResearch Corporation
InventorsRichard W. Compans, Ranjit Ray
Life of this patent
Estimating the term…
Abstract
The present invention relates to a vaccine composition useful in preparation of virus-caused disease comprising as its active agent at least one immunogenically effective amount of immunogenic viral envelope glycoprotein complexed with a lipid.
Claims19
A vaccine composition useful in prevention of virus-caused disease comprising, as an active agent, an immunogenically effective amount of at least one immunogenic (F) fushion viral envelope glycoprotein from said virus complexed with a lipid, and a pharmaceutically acceptable carrier.
A vaccine composition useful in prevention of virus-caused disease comprising, as an active agent, an immunogenically effective amount of at least one immunogenic (HN) receptor-binding viral envelope glycoprotein from said virus complexed with a lipid, and a pharmaceutically acceptable carrier.
A vaccine composition useful in prevention of virus-caused disease comprising, as an active agent, an immunogenically effective amount of at least one immunogenic (F) fushion viral envelope glycoprotein and at least one immunogenic (HN) receptor-binding viral envelope glycoprotein from said virus complexed with a lipid, and a pharmaceutically acceptable carrier.
A vaccine composition prepared by dialyzing a solution comprising a dialyzable detergent, at least one solublizied fusion glycoprotein, and solubilized lipid, so that a gylcoprotein lipid complex is formed, and combining said complex with a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.