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US 4,789,745 AGranted
Certain 3-[3-(3-pyridinyloxy)propoxy or propylthio]-acetic acid derivatives which are useful as synthetase inhibitors
AssigneeThe Upjohn Company
InventorChiu-Hong Lin
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Abstract
The present invention provides novel .omega.-(3-pyridynl) oxa-, thia-, and aza- alkanoic acids and esters thereof, which are useful as thromboxane A.sub.2 (TXA.sub.2) inhibitors and as such represent potent pharmacological agents.
Claims4
A compound represented by the structural formula:
- wherein Y.sub.1 is
- (a) --O-- or
- (b) --S--;
- and
- wherein Q.sub.1 is
- (a) --CH.sub.2 CH.sub.3, or
- (b) --CO.sub.2 CH.sub.2 CH.sub.3 ;
- and
- pharmacologically acceptable salts thereof.
6 more elements
Dependencies are inferred from the claim text.