Bone morphogenetic protein composition
AssigneeThe Regents of the University of California
InventorMarshall R. Urist
Life of this patent
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Abstract
BMP compositions including the human factor and bovine factor thereof, the process of isolating BMP compositions and factors, and the use of such factors and compositions to induce bone formation in animals.
Claims3
The process of inducing bone formation in animals comprising the steps of implanting into said animals substantially pure BMP compositions comprising BMP factor and at least one BMP associated protein selected from a group consisting of BMP associated proteins having molecular weights in the range of between about 24 kDa and about 34 kDa, said BMP factor being capable of inducing bone formation independent of the presence of said BMP associated proteins, and said BMP associated proteins being incapable of inducing bone formation independent of the presence of said BMP factor.
Dependencies are inferred from the claim text.