Method for the treatment of periodontal pockets with a composition comprising collagen and an antiseptic or anti-inflammatory substance
AssigneePierre Fabre Medicament
InventorsGenevieve Thomas-Leurquin, Anne Gayot, Pierre Poitou, Serge Basquin
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Abstract
The present invention relates to a composition consisting of an association of collagen with an antiseptic and/or antiinflammatory active principle, the process for its preparation and its use for the production of a pharmaceutical composition. The pharmaceutical composition according to the invention comprises collagen as the vehicle and at least one antiseptic and/or inflammatory substance as the active principle. Application to the topical treatment of periodontal complaints.
Claims10
The method of treating a patient having at least one periodontal pocket which comprises introducing into said pocket a pharmaceutical composition comprising collagen as the vehicle and at least one antiseptic or anti-inflammatory substance as the active principle and maintaining said pharmaceutical composition in said pocket until said collagen is absorbed therefrom, said composite being in a flexible form.
A method as claimed in 1 wherein said pharmaceutical composition is prepared by the following steps:
- (a) the collagen is solubilized in acetic acid until a solution with a collagen concentration of between 0.5 g and 5 per 100 g of solution is obtained;
- (b) the active principle is solubilized in distilled water until a solution with an active principle concentration of between 1 g and 2 g per 100 g of solution is obtained;
- and
- (c) the two solutions obtained after steps (a) and (b) are mixed together and the solvents are then removed.
Dependencies are inferred from the claim text.