De-(acetylglucosaminyl)-di(dehydro)-deoxy teicoplanin derivatives
AssigneeGruppo Lepetit S.p.A.
InventorsAdriano Malabarba, Aldo Trani, Pietro Ferrari, Giorgio Tarzia
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Abstract
The present invention is directed to new de-(acetylglucosaminyl-di(dehydro)deoxy teicoplanin derivatives which possess antibiotic activity mainly against gram positive bacteria. The new compounds are obtained by chemical modification of a teicoplanin antibiotic substance.
Claims4
A de-(acetylglucosaminyl)-di(dehydro)-deoxy teicoplanin derivative of formula I ##STR3## wherein, x and y each represents nil or an additional bond, A represents hydrogen or N[(C.sub.10 -C.sub.11)aliphatic acyl]-.beta.-D-2-deoxy-2-aminoglucopyranosyl, M represents hydrogen or .alpha.-D-mannopyranosyl, R.sup.o represents nil when y represents an additional bond, and hydrogen when y represents nil, with the proviso that when x represents an additional bond y must represent nil, and when x represent nil y must represent an additional bond and that when M represents hydrogen also A must represent hydrogen, and the addition salts thereof.
Dependencies are inferred from the claim text.