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US 4,789,542 AGranted
Radioiodinated glucose analogues for use as imaging agents
AssigneeThe United States of America as represented by the United States Department of Energy
InventorsMark M. Goodman, Furn F. Knapp, Jr.
Life of this patent
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Abstract
A radioiodinated branched carbohydrate for tissue imaging. Iodine-123 is stabilized in the compound by attaching it to a vinyl functional group that is on the carbohydrate. The compound exhibits good uptake and retention and is promising in the development of radiopharmaceuticals for brain, heart and tumor imaging.
Claims7
An imaging agent comprising:
- an administering medium suitable for intravenous injection and a compound comprising a glucose analogue to which is covalently attached a vinyl functional group to which is covalently attached the radioisotipe I-123, said compound being present in an amount sufficient to produce a radioimage of tissue using radioimaging techniques.
Dependencies are inferred from the claim text.