Pharmaceutical compositions comprising calcitonin and an absorption-promoting substance
AssigneeYamanouchi Pharmaceutical Co., Ltd.
InventorsSeiya Kagatani, Shunji Hasumi, Takashi Sonobe, Masayoshi Aruga
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Abstract
Pharmaceutical compositions for intranasal administration comprising (a) calcitonin and (b) at least one absorption enhancer selected from the group consisting of benzyl alcohol, ethanol, thiamine or a salt thereof, salicylic acid or a salt thereof, capric acid or a salt thereof, Macrogol 400, pyridoxal or a salt thereof, malic acid or a salt thereof and pyrophosphoric acid or a salt thereof, in (c) a liquid diluent or carrier, suitable for application to the nasal mucosa.
Claims6
An intranasal pharmaceutical composition of calcitonin suitable for applying to nasal mucous membrane, said composition comprised of (a) from about 200 to 6000 IU/ml of calcitonin, (b) from about 0.05 to about 15 weight percent by volume of an absorption enhancer consisting of salicylic acid or a salt thereof, and (c) a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.