Pharmacologically active amides, processes for their preparation and pharmaceutical compositions containing them

A pharmaceutical composition containing in association with one or more diluents or adjuvants which are compatible and pharmaceutically acceptable, at least one active ingredient of formula:

• ##STR47## in which Q.sub.1 denotes nitrogen,
• Q.sub.2 denotes nitrogen,
• Z.sub.1 and Z.sub.2, which may be identical or different, denote hydrogen, halogen, alkyl or alkoxy of 1 to 3 carbon atoms each, nitro, or trifluoromethyl, Z is bound in the ortho or para position with respect to Q.sub.2 and deontes phenyl, thienyl, pyridyl or phenyl substituted by one or two substituents chosen from halogen, alkyl and alkoxy of 1 to 4 carbon atoms each, trifluoromethyl and nitro, the chain--X--(CH.sub.2).sub.n --(CHR).sub.m --CO--NR.sub.1 R.sub.2 is bound in the ortho position or para position with respect to Q.sub.2, R denotes hydrogen or alkyl of 1 to 3 carbon atoms, R.sub.1 and R.sub.2, which may be identical or different, denote a linear or branched alkyl of 1 to 6 carbons atoms each, cycloalkyl of 3 to 6 carbon atoms, phenyl, phenylalkyl or cycloalkylalkyl in each of which the alkyl contains 1 to 3 carbon atoms and in which the cycloalkyl contains 3 to 6 carbon atoms or an alkenyl of 3 to 6 carbon atoms in which the double bond is not situated in the 1,2 position with respect to the nitrogen atom,
• R.sub.1 and R.sub.2 can also form, together with the nitrogen atom to which they are attached, a pyrrolidien, piperidine, morpholine or thiomorpholine ring,
• X denotes >CH--R.sub.3, >N--R.sub.4, >SO or >SO.sub.2, oxygen, or sulphur,
• R.sub.3 denotes hydrogen or alkyl of 1 to 3 carbon atoms,
• R.sub.4 denotes alkyl of 1 to 3 carbon atoms,
• m is 0 or 1, and
• n is 0, 1 or 2,
• provided that, when X denotes >SO, >SO.sub.2 or >N--R.sub.4, the sum m+n is equal to at least 1, and, when Z is in the para position with respect to Q.sub.2, X cannot denote >CH--R.sub.3, or a mixture of stereoisomeric compounds of formula (I), or, where it can exist, a salt of such a compond or of a mixture of stereoisomeric compounds with a pharmaceutically acceptable acid.