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US 4,788,064 AGranted
Transdermal delivery system
AssigneeWarner-Lambert Company
InventorsNiranjan M. Patel, Mohan B. Kabadi, Susan C. Moniot
Life of this patent
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Abstract
The administration of a bronchodilator to a subject can be carried out using a new transdermal delivery system, a multilayer laminate where the drug is mixed in a gel which must pass through a barrier membrane prior to administration on the skin.
Claims7
A multi-layered device for the transmembranal delivery of procaterol comprising:
- an impermeable backing whose perimeter contains an adhesive;
- a composition saturated in a synthetic sponge layered on the inside of the backing wherein the composition comprises
- (a) about 0.1 to about five weight percent procaterol or pharmaceutically acceptable salt thereof;
- (b) about five to about 30 weight percent of an essential fatty acid;
- (c) about 15 to about 40 weight percent of a solvent for (a), and
- (d) about 25 to about 55 weight percent of a cosolvent for (a);
- a porous barrier membrane covering the composition;
- and a release liner covering in turn the barrier membrane and adhered to the backing.
5 more elements
Dependencies are inferred from the claim text.