Amino substituted benzenepropanols
AssigneeE. R. Squibb & Sons, Inc.
InventorsDavid M. Floyd, Spencer D. Kimball, Steven Brandt
Life of this patent
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Abstract
Hypotensive activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein R.sub.1 is hydrogen or alkyl; R.sub.2 and R.sub.3 are each independently phenyl, substituted phenyl, cycloalkyl, or R.sub.2 is hydrogen and R.sub.3 is heteroaryl; R.sub.4 and R.sub.5 are the same or different and each is hydrogen, hydroxy, alkoxy, alkanoyl or alkyl; R.sub.6 is hydrogen or alkyl; and n is 1, 2, 3 or 4; with the proviso that if R.sub.2 and R.sub.3 are each phenyl, at least one of R.sub.1, R.sub.4, R.sub.5 and R.sub.6 is other than hydrogen.
Claims12
A compound having the formula ##STR16## or a pharmaceutically acceptable salt thereof, wherein R.sub.1 is hydrogen or alkyl;
- R.sub.2 and R.sub.3 are each independently cycloalkyl;
- R.sub.4 and R.sub.5 are the same or different and each is hydrogen, hydroxy, alkoxy, alkanoyl or alkyl;
- R.sub.6 is hydrogen or alkyl;
- and
- n is 1, 2, 3 or 4.
Dependencies are inferred from the claim text.