Direct fluorination of substituted pyridines
AssigneeAllied-Signal Inc.
InventorsMichael Van Der Puy, Richard E. Eibeck
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Abstract
Substituted pyridine compounds particularly alkyl-substituted pyridines, are directly fluorinated to the corresponding 2-fluoro alkyl-substituted pyridines. Fluorine gas, preferably diluted with an inert gas, is passed into the substituted pyridine, preferably in a solvent, at a temperature of +25.degree. C. to -40.degree. C., preferably about -25.degree. C.
Claims18
A process for producing 2-fluoro substituted pyridine compounds comprising contacting a pyridine compound selected from the group consisting of pyridines substituted with C.sub.1 to C.sub.8 alkyl, aralkyl, aryl, Cl, acetyl, carbomethoxy. and cyano with diluted gaseous fluorine at a temperature of +25.degree. to -40.degree. C.
Dependencies are inferred from the claim text.