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US 4,786,723 AGranted
7-hydroxyguanine compounds, process for preparing said compounds, and anti-tumor agent containing the same
AssigneeKanegafuchi Chemical Industry Co., Ltd.
InventorsMikio Kitahara, Kiyoto Ishii, Hajime Kawaharada, Kiyoshi Watanabe
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Abstract
Novel 7-hydroxyguanine compounds of the formula: ##STR1## wherein R is hydrogen atom or hydroxy, and a salt thereof, which have excellent anti-tumor activity, process for preparing the compounds, and anti-tumor agent containing said compound as an active ingredient.
Claims4
A 7-hydroxyguanine compound of the formula:
- ##STR6## wherein R is hydrogen or hydroxy, and a salt thereof.
An anti-leukemia composition which comprises as an active ingredient an effective amount of a 7-hydroxyguanine compound of the formula:
- ##STR7## wherein R is hydrogen or hydroxy, or a pharmaceutically acceptable salt thereof in admixture with a pharmaceutically acceptable carrier or diluent.
Dependencies are inferred from the claim text.