Method for eliciting anxiolysis
AssigneesUniversity of Florida, Pharmatec, Inc.
InventorsJames W. Simpkins, Warren C. Stern
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Abstract
The invention provides a method for relieving anxiety in a mammal using a compound of the formula ##STR1## wherein R is Benzyl or cyclohexyl, or a non-toxic pharmaceutically acceptable salt thereof. A preferred compound for use in the subject method is 1-methyl-3-{N-[(3'-benzyloxycarbonyl)propyl]}carbamoyl-1,4-dihydropyridine .
Claims4
A method of relieving anxiety without causing significant sedation in a mammal, said method comprising administering to a mammal in need of such treatment an anxiolytically effective, non-sedating amount of a compound of the formula ##STR10## wherein R is benzyl or cyclohexyl, or a non-toxic pharmaceutically acceptable salt thereof.
A method of relieving anxiety without causing significant sedation in a mammal, said method comprising administering to a mammal in need of such treatment an anxiolytically effective, non-sedating amount of 1-methyl-3{N-[(3'-benzyloxycarbonyl)propyl]}carbamoyl-1,4-dihydropyridine or a non-toxic pharmaceutically acceptable salt thereof.
A method of relieving anxiety without causing significant sedation in a mammal, said method comprising administering to a mammal in need of such treatment a pharmaceutical composition in dosage unit form comprising, per dosage unit:
- (a) an anxiolytically effective, non-sedating amount of a compound of the formula ##STR11## wherein R is benzyl or cyclohexyl, or a non-toxic pharmaceutically acceptable salt thereof;
- and (b) a non-toxic pharmaceutically acceptable carrier therefor.
Dependencies are inferred from the claim text.