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US 4,786,508 AGranted
Coated dosage forms
AssigneeWarner-Lambert Company
InventorsIsaac Ghebre-Sellassie, Robert Gordon, Maryann Mench, Russell U. Nesbitt, Jr., Mary E. Trapold
Life of this patent
Estimating the term…
Abstract
Aqueous solutions of certain cationic (meth)acrylic ester copolymers can be used to coat dosage forms to taste- and odor-mask bio-active agents therein. Pellets are highly preferred dosage forms.
Claims5
A pharmaceutical substance in oral dosage form having a saliva resistant-acid soluble coating, said coating comprising:
- (a) a polymeric component containing a cationic copolymer which contains residues of (meth)acrylic esters and dimethyl aminoethyl (meth)acrylate, said coating deposited from an aqueous acidic solution having a pH between 1 and 6.
A pharmaceutical substance wherein the oral dosage form is a pellet having an average diameter of 0.35 mm to 1.00 mm.
A dosage form wherein the pharmaceutical substance is acetaminophen.
Dependencies are inferred from the claim text.