Therapeutic agents

A method according to claim 6 wherein the fatty acid esters have HLB value of at least 12.

A method of effecting analgesia in humans and animals which comprises orally administering to a human or animal in need thereof an analgesically effective amount of 2-(2-fluoro-4-biphenylyl)propionic acid or a pharmaceutically acceptable salt thereof and an amount of excipient sufficient to produce a rapid release of the active agent into the human or animal, said excipient being one suitable for formulating solid orally administerable pharmaceutical compositions and further being a fatty acid ester which comprises one or more polyol esters and glycerides of natural vegetable oil fatty acids, said excipient having a melting point in the range of 30.degree.-50.degree. C. and an HLB value of at least 10.

A solid pharmaceutical composition in oral administration form useful for treating pain, inflammation and fever in humans and animals, which comprises 2-(2-fluoro-4-biphenylyl)propionic acid or a pharmaceutically acceptable salt thereof and an amount of excipient sufficient to produce a rapid release of the active agent into the human or animal, said excipient being one suitable for formulating solid orally administerable pharmaceutical compositions and further being a fatty acid ester which comprises one or more polyol esters and glycerides of natural vegetable oil fatty acids, said excipient having a melting point in the range of 30.degree.-50.degree. C. and an HLB value of at least 10.