N-substituted 2-amino-thiazoles, process for their preparation and their therapeutic application

Abstract

The subject of the invention is N-substituted 2-aminothiazoles of formula ##STR1## in which: X is a C--H group or a nitrogen atom, R.sub.1 and R.sub.2 are, independently of each other, a hydrogen atom, a halogen atom or an alkyl, alkoxy, alkylthio, alkenyloxy, cycloalkyl, trifluoromethyl, nitro, amino, (C.sub.1 -C.sub.6 alkyl)amino or di(C.sub.1 -C.sub.6 alkyl)-amino radical, and R.sub.3 is a hydrogen atom, a --CH.sub.2 --OH group or a --COOR.sub.4 group, R.sub.4 being a hydrogen atom or an alkyl group, and also the pharmaceutically acceptable salts thereof. These compounds have an anti-inflammatory and antiallergic activity and can be used in therapy, especially in the ocular field.

Dependencies are inferred from the claim text.