Triazole containing diphosphonate compounds and the use thereof

A method for the treatment of calcium metabolism disturbances comprising administering to a subject an effective amount of a compound of the formula:

• ##STR11## wherein Het is a substituted or unsubstituted heterocyclic ring selected from the group consisting of 1,2,3-trizole and 1,2,4-triazole, and wherein the substituents are selected from the group consisting of C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, halogen selected from the group consisting of fluorine, chlorine, bromine, iodine;
• hydroxyl, carboxyl, an amino group optionally substituted by C.sub.1 -C.sub.4 alkyl or alkanoyl of 1 to 6 carbon atoms;
• benzyl and benzyl substituted by C.sub.1 -C.sub.4 alkyl, nitro, amino and aminoalkyl with 1 to 4 carbon atoms,
• A is a straight-chained or branched, saturated or unsaturated hydrocarbon chain containing 2 to 8 carbon atoms,
• X is a hydrogen atom, hydroxy optionally substituted by alkanoyl of 1 to 6 carbon atoms or an amino group optionally substituted by an alkyl radical of 1 to 4 carbon atoms or by alkanoyl of from 1 to 6 carbon atoms and R is a hydrogen atom or an alkyl of 1 to 4 carbon atoms or a pharmaceutically acceptable salt thereof.