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US 4,774,179 AGranted
Process for preparing a 7-aminocephalosporanic acid compound
AssigneeAsahi Kasei Kogyo Kabushiki Kaisha
InventorsShigeaki Ichikawa, Keizou Yamamoto, Kenji Matsuyama
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Abstract
A process for preparing a 7-aminocephalosporanic acid compound which comprises treating a cephalosporin C compound with an enzyme-producing microorganism belonging to the genus Pseudomonas or a material obtained by subjecting the microorganism to chemical and/or physical treatment. A direct hydrolysis of the cephalosporin C compound into the 7-aminocephalosporanic acid compound and D-.alpha.-aminoadipic acid can be attained by the microorganism or material.
Claims3
A process for preparing a 7-aminocephalosporanic acid compound of the formula:
- ##STR3## wherein R represents --OCOCH.sub.3, --H or --OH, which comprises treating in an aqueous medium a cephalosporin C compound of the formula:
- ##STR4## wherein R is as defined above, or a salt thereof, with a microorganism selected from the group consisting of Pseudomonas sp. SE-83 (Fermentation Research Institute Accession No. FERM BP-817) and Pseudomonas sp. SE-495 (Fermentation Research Institute Accession No. FERM BP-818), or with a material obtained by subjecting the microorganism to chemical and/or physical treatment.
Dependencies are inferred from the claim text.