Fluoroalkoxy substituted benzimidazoles useful as gastric acid secretion inhibitors
AssigneeByk Gulden Lomberg Chemische Fabrik GmbH
InventorsBernhard Kohl, Ernst Sturm, Georg Rainer
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AssigneeByk Gulden Lomberg Chemische Fabrik GmbH
InventorsBernhard Kohl, Ernst Sturm, Georg Rainer
Estimating the term…
Dialkoxypyridines of formula I ##STR1## wherein R1 is 1-3C-alkyl which is completely or predominantly substituted by fluorine, or a chlorodifluoromethyl radical and R1' is hydrogen, halo, trifluoromethyl, 1-3C-alkyl, or 1-3C-alkoxy which is optionally completely or predominantly substituted by fluorine, or R1 and R1', together with the oxygen atom to which R1 is bonded, are 1-2C-alkylenedioxy, which is optionally completely or partly substituted by fluorine, or chlorotrifluoroethylenedioxy, R3 is 1-3C-alkoxy, one of R2 and R4 is 1-3C-alkoxy and the other is a hydrogen atom or 1-3C-alkyl and n is 0 or 1, and salts thereof are new compounds with a pronounced protective action on the stomach. Processes for preparing these compounds, medicaments containing them and their use, as well as intermediate compounds and their use for preparing the subject dialkoxypyridines, are disclosed.
A dialkoxypyridine of formula I ##STR10## wherein R1 is 1-3C-alkyl which is completely or predominantly substituted by fluorine, or chlorodifluoromethyl;
Dependencies are inferred from the claim text.