Microencapsulated medicament in sweet matrix
AssigneeBio-Dar Ltd.
InventorAvner Rotman
Life of this patent
Estimating the term…
Abstract
Any orally administrable medicament is prepared into a dosage form which eliminates the unpleasant taste and mouth feel of the medicament and is easily and pleasantly ingested even by children, by microencapsulating the medicament into microcapsules of less than 300 microns diameter, and embedding the microcapsules into a soft, sweet, palatable matrix, such as chocolate.
Claims10
A sustained release unit dosage form for oral administration to human patients of a large dosage designed for gradual release of a pharmaceutically active principle which could cause a serious overdose if released immediately if not in sustained release form, comprising:
- a soft, sweet, palatable matrix which is sufficiently soft to allow mastication thereof without the necessity of substantial chewing, said matrix having substantially homogenously embedded therein macrocapsules of a large sustained release dosage of active principle, said microcapsules having a diameter below about 300 microns, and being present in said matrix in a quantity sufficient to provide a sustained release unit dose of said active principle in each bite-size unit of said matrix, said microcapsules being microencapsulated in gastric resistant sustained release material.
Dependencies are inferred from the claim text.