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US 4,747,881 AGranted
Ingestible aggregate and delivery system prepared therefrom
AssigneeWarner-Lambert Company
InventorsJames J. Shaw, Shri C. Sharma
Life of this patent
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AssigneeWarner-Lambert Company
InventorsJames J. Shaw, Shri C. Sharma
Estimating the term…
The present invention relates to an ingestible aggregate comprising a pre-swelled substantially anhydrous hydrocolloid and a substrate. More particularly this invention relates to an aggregate having as a substrate a dietary fiber and/or drug wherein the composition can be administered in a therapeutically effective amount. Hydrocolloids useful include natural and modified gums, celluloses, modified celluloses, pectins, mucillages, modified starches, noncellulose polysaccharides, algal polysaccharides and mixtures thereof. The aggregate should be in the size range of about 4 to about 70 U.S. mesh. The unpleasant taste and mouthfeel of the fiber and/or drug is effectively masked and substantial hydration is delayed until the compositions reaches the stomach. The compositions are substantially more palatable, devoid of grainless, bitterness or fibrous texture. The pleasant taste of the composition encourages patient compliance with their fiber or drug therapy.
An ingestible substantially anhydrous aggregate comprising a pre-swelled hydrocolloid and a solid substrate, wherein the hydrocolloid at least partially entraps and binds the substrate, the substrate comprising soluble dietary fiber and wherein the substrate and the hydrocolloid are not the identical material.
An ingestible aggregate consisting essentially of a pre-swelled substantially anhydrous hydrocolloid and a substrate particle wherein the hydrocolloid at least partially entraps and binds substrate particles wherein the substrate is a soluble dietary fiber selected from the group consisting of locust bean gum, guar gum, acacia gum and mixtures thereof;
Dependencies are inferred from the claim text.