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US 4,738,932 AGranted
Reaginic test for syphilis
AssigneeAdvanced Polymer Systems, Inc.
InventorKenichi K. Yabusaki
Life of this patent
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Abstract
A reaginic agglutination test for syphilis-associated antibodies is disclosed. The test uses an antigen reagent that comprises a buffered aqueous suspension of cardiolipin antigen ionically coupled to latex particles via a polypeptide bridge. Positive sera react with the antigen reagent and yield an agglutination pattern characterized by medium to large aggregates. Negative sera yield no agglutinated particles.
Claims25
An antigen reagent for use in a reaginic test for syphilis comprising an aqueous suspension of cardiolipin antigen ionically coupled to latex particles via a positively charged polypeptide bridge.
Dependencies are inferred from the claim text.