Arylthio piperidinamide of (4-quinolinylamino)benzoic acid and S-oxidized derivatives

Abstract

This invention provides a piperidine compound of the formula: ##STR1## wherein R.sup.1 is hydrogen or trihalomethyl, R.sup.2 is hydrogen or protected carboxy, R.sup.3 is heterocyclic group or aryl which may be halogen substituted, and X is --S--, ##STR2## --O--, --NH-- or lower alkylene which may be hydroxy substituted, and pharmaceutically acceptable salt thereof, These compounds possess hypotensive activity and are useful as anti-hypertensive agents. The invention further relates to processes for the preparation of these compounds and pharmaceutical compositions comprising compounds of the above formula.

Dependencies are inferred from the claim text.