2-aminothiazolyl-containing .beta.-lactam antibiotics
AssigneeBayer Aktiengesellschaft
InventorsMichael Boberg, Karl G. Metzger, Hans-Joachim Zeiler
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Abstract
Antibiotically active penicillins and cephalosporins of the formula ##STR1## in which Z is hydrogen or lower alkoxy, n is 1 or 2, Y, in the form of the free acid, is ##STR2## X is --S--, --n--, --SO-- or --SO.sub.2 --, T is an organic radical, hydrogen or halogen, A is hydroxyl, optionally substituted alkyl, a substituted or unsubstituted phenyl ring, an optionally substituted polycyclic aromatic ring, an optionally substituted 5-membered or 6-membered heterocyclic ring with nitrogen, oxygen and/or sulphur as hetero atoms in the ring, or an optionally substituted polycyclic heterocyclic ring, or non-toxic pharmaceutically tolerated salts thereof.
Claims12
A compound of the formula ##STR38## in which Z is hydrogen or lower alkoxy,
- n is 1 or 2,
- Y, in the form of the free acid is ##STR39## X is --S--, --SO-- or SO.sub.2 --, T denotes hydrogen, halogen or a radical ##STR40## and in which A denotes lower alkyl having up to 6 carbon atoms or unsubstituted phenyl
- or a non-toxic pharmaceutically tolerated salt thereof.
Dependencies are inferred from the claim text.