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US 4,734,413 AGranted
Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators
AssigneeRiker Laboratories, Inc.
InventorJames J. Wade
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Abstract
Substituted 1,2,4-triazolo[1,5-a]triazines as bronchodilators are disclosed. Pharmaceutical formulations comprising such compounds and pharmacological methods of using such compounds are also described.
Claims7
A compound of the formula ##STR62## wherein R.sub.2 is hydrogen, lower alkyl, or phenyl;
- R.sub.5 is lower alkyl;
- and R.sub.7 is methoxy, methylthio or ##STR63## wherein X is independently oxygen, sulfur, methylene, imido or lower N-alkylimido;
- or a pharmaceutically acceptable acid-addition salt thereof.
A method for obtaining bronchodilation in a mammal, comprising administering a compound of the formula ##STR64## wherein R.sub.2 is hydrogen, lower alkyl, or phenyl;
- R.sub.5 is lower alkyl;
- and R.sub.7 is methoxy, methylthio or ##STR65## wherein X is independently oxygen, sulfur, methylene, imido or lower N-alkylimido;
- or a pharmaceutically acceptable acid-addition salt thereof;
- said compound being administered in an amount sufficient to cause bronchodilation.
1 more element
Dependencies are inferred from the claim text.