Lipoxygenase inhibitor

A lipoxygenase inhibitor composition comprising as active ingredient a lipoxygenase inhibiting effective amount of a substituted styrene derivative having formula (I) ##STR20## wherein X represents a hydroxyl group or a lower alkoxy group, q is an integer of 2 or 3;

• and Y represents a member selected from the group consisting of --COOR.sub.1 wherein R.sub.1 represents an alkyl group having 4 to 10 carbon atoms, which may be substituted by halogen(s);
• ##STR21## wherein R.sub.2 and R.sub.3 each represents a hydrogen atom, a lower alkoxy group or a hydroxyl group and Z represents a radical of the formula, --O--(CH.sub.2).sub.n --CH.dbd.CH--, --NH--(CH.sub.2).sub.n --CH.dbd.CH-- or --NH--(CH.sub.2).sub.n --, wherein n is an integer of 1 to 4;
• --CO--NH--C.sub.m H.sub.2m+1 wherein m is an integer of 6 to 14;
• --CO--(CH.sub.2).sub.1 --R.sub.4 wherein R.sub.4 represents a phenyl group which may be substituted by a hydroxyl group, a lower alkoxy group or a halogen atom, or a hydrogen atom and 1 is zero or an integer of 1 to 7, said 1 being an integer of 1 to 7 when said R.sub.4 represents a hydrogen atom;
• and --C.sub.p H.sub.2p --R.sub.5 wherein R.sub.5 represents a hydrogen atom or a ##STR22## wherein R.sub.6 and R.sub.7 each represents a hydrogen atom, a hydroxyl group, a lower alkoxy group or a halogen atom and p is an integer of 1 to 8 when R.sub.5 is a hydrogen atom, and zero or an integer of 1 to 5 when R.sub.5 is ##STR23## and a pharmaceutically acceptable carrier.