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US 4,732,983 AGranted
Pyschotropic polycyclic imides
AssigneeAmerican Home Products Corporation
InventorsGary P. Stack, Guy A. Schiehser, Magid A. Abou-Gharbia
Life of this patent
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Abstract
Substituted imides of the following formulae are antipsychotic, anxiolytic agents with very little extrapyramidal side effects: ##STR1## in which n is one of the integers 2, 3, 4 or 5; R is phenyl, halophenyl, trifluoromethylphenyl, alkoxyphenyl in which the alkoxy substituent contains 1 to 3 carbon atoms, 2-pyrimidinyl halopyrimidin-2-yl, 2-pyrazinyl, halopyrazin-2-yl, 2-pyridinyl, halopyridin-2-yl, cyanopyridin-2-yl, quinolyl, or haloquinolyl; and the dotted lines represent optional unsaturation; or a pharmaceutically acceptable salt thereof.
Claims8
A compound of the formulae:
- ##STR6## in which n is one of the integers 2, 3, 4 or 5;
- R is phenyl, halophenyl, trifluoromethylphenyl, alkoxyphenyl in which the alkoxy substituent contains 1 to 3 carbon atoms, 2-pyrimidinyl, halopyrimidin-2-yl, 2-pyrazinyl, halopyrazin-2-yl, 2-pyridinyl, halopyridin-2-yl, cyanopyridin-2-yl, quinolyl, or haloquinolyl;
- and the dotted lines represent optional unsaturation;
- or a pharmaceutically acceptable salt thereof.
1 more element
Dependencies are inferred from the claim text.