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US 4,732,969 AGranted
Des-19-leucine, 20-glutamine-calcitonin
AssigneeArmour Pharmaceutical Company
InventorsRonald C. Orlowski, Jay K. Seyler, James E. Geever
Life of this patent
Estimating the term…
Abstract
New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a leucine in position 19 or a glutamine in position 20. Both amino acids are omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.
Claims9
des-19-leucine, 20-glutamine-Calcitonin, wherein the calcitonin is salmon, eel or chicken.
A peptide having the structure:
- ##STR26##
A peptide having the structure:
- ##STR27## where R.sub.1 is S-n-alkyl, Cys or H and R.sub.2 is S-n-alkyl or H, R.sub.1 being S-n-alkyl, Cys or H when R.sub.2 is H and R.sub.2 being S-n-alkyl or H when R.sub.1 is H.
Dependencies are inferred from the claim text.