Certain pyridyl, thienyl or furyl propenoic acids or esters having anti-inflammatory anti-allergic properties
AssigneeBeecham Group Limited
InventorDerek R. Buckle
Life of this patent
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Abstract
Compounds of formula (I): ##STR1## in which R.sub.1 is hydrogen or C.sub.1-6 alkyl; R.sub.2 is hydrogen or a group --CO.sub.2 R.sub.3 where R.sub.3 is hydrogen or C.sub.1-6 alkyl; n is an integer of from 2 to 12; X represents a double or triple bond, and each of A and B represents hydrogen when X is a double bond, or both A and B are absent when X is a triple bond; and ##STR2## represents an aromatic heterocyclic ring, are disclosed as inhibitors of 5-lipoxygenase.
Claims12
A compound of the formula ##STR19## wherein R.sub.1 is hydrogen or C.sub.1 -C.sub.6 alkyl;
- R.sub.2 is hydrogen;
- n is an integer of from 2 to 12;
- ##STR20## represents pyridyl, thienyl or furyl or a pharmaceutically acceptable salt thereof.
A compound 3-[3-(1-tridecynyl)-2-furanyl]prop-2-enoic acid or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.