Multilayered chemical analysis material for analysis of aqueous liquids

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a reagent layer;
• (c) a radiation-blocking layer;
• and
• (d) a porous, sample spreading layer;
• (i) said reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate,
• (ii) urease incorporated in the reagent layer (b) or in a layer immediately adjacent the reagent layer (b), and
• (iii) a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt, incorporated in at least one of the reagent layer (b) and a layer immediately adjacent the reagent layer (b).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a layer of a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• (c) a reagent layer;
• and
• (d) a radiation blocking layer;
• and
• (e) a porous, sample-spreading layer;
• with
• (i) said reagent layer (c) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate, and
• (ii) urease incoporated in the reagent layer (c) or in a layer immediately adjacent the reagent layer (c).

A multi-layered, chemical anaylsis element for analysis of an aqueous liquid, which comprises

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a layer of a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• (c) a reagent layer;
• and
• (d) a porous, sample-spreading layer;
• with
• (i) said reagent layer (c) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate, and
• (ii) urease incorporated in the reagent layer (c) or in a layer immediately adjacent the reagent layer (c).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a reagent layer;
• (c) an adhesive layer;
• and
• (d) a porous, sample-spreading layer;
• with
• (i) said reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate,
• (ii) urease incoporated in the reagent layer (b) or in a layer immediately adjacent the reagent layer (b), and
• (iii) a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt, incorporated in at least one of the reagent layer (b) and a layer immediately adjacent the reagent layer (b).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a reagent layer;
• (c) a radiation-blocking layer,
• (d) an adhesive layer;
• and
• (c) a porous, sample-spreading layer;
• with
• (i) said reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate,
• (ii) urease incorporated in the reagent layer (b) or in a layer immediately adjacent the reagent layer (b), and
• (iii) a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt, incorporated in at least one of the reagent layer (b) and a layer immediately adjacent the reagent layer (b).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a reagent layer;
• (c) a layer of a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• (d) a radiation-blocking layer;
• and
• (e) a porous, sample-spreading layer;
• with
• (i) said reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate, and
• (ii) urease incorporated in the reagent layer (b) or in a layer immediately adjacent the reagent layer (b).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a reagent layer;
• (c) a layer of a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• and
• (d) a porous, sample-spreading layer;
• with
• (i) said reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate, and
• (ii) urease incorporated in the reagent layer (b) or in a layer immediately adjacent the reagent layer (b).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a reagent layer;
• (c) a layer of a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• (d) an adhesive layer;
• and
• (e) a porous, sample-spreading layer;
• with
• (i) said reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate, and
• (ii) urease incorporated in the reagent layer (b) or in a layer immediately adjacent the reagent layer (b).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a layer of a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• (c) a reagent layer;
• (d) an adhesive layer;
• and
• (e) a porous, sample-spreading layer;
• with
• (i) said reagent layer (c) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate, and
• (ii) urease incorporated in the reagent layer (c) or in a layer immediately adjacent the reagent layer (c).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a reagent layer;
• (c) a layer of a member selecteed from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• (d) a radiation-blocking layer;
• (e) an adhesive layer;
• and
• (f) a porous, sample-spreading layer;
• with
• (i) said reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate,
• (ii) urease incorporated in the reagent layer (b) or in a layer immediately adjacent the reagent layer (b).

A multi-layered, chemical analysis element for analysis of an aqueous liquid, which comprises:

• (a) a light-transmitting, water impermeable support having provided thereon in sequence and without any intermediate layer;
• (b) a layer of a member selected from the group consisting of a lake forming metal salt and a lake forming metal oxide selected from the group consisting of TiO.sub.2, SiO.sub.2, Al.sub.2 O.sub.3 and an EDTA metal salt;
• (c) a reagent layer;
• (d) a radiation-blocking layer;
• (e) an adhesive layer;
• and
• (f) a porous, sample-spreading layer;
• with
• (i) said reagent layer (c) containing a lake dye precursor dispersed in a hydrophilic binder, wherein said lake dye precursor is haematoxylin, brazilin, dithizone, diphenylcarbazide, oxine, rubeanic acid, formaldoxime, dimethylglyoxime, alizarin, or sodium rhodinate, and
• (ii) urease incorporated in the reagent layer (c) or in a layer immediately adjacent the reagent layer (c).