Implantable chemoattractant system
AssigneeChildren's Medical Center Corporation
InventorsBruce R. Zetter, Robert S. Langer
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Abstract
A system for providing sustained prolonged release of a chemoattractant to a surrounding biological medium which contains cells responsive to the chemoattractant. The system consists of a biocompatible, non-inflammatory body, which sequesters the chemoattractant and allows sustained prolonged release of the chemoattractant from at least one part of the body. A cell trap is positioned adjacent to the releasing portion of the body, so that the released chemoattractant is transmitted through the trap and attracted cells are trapped in it.
Claims16
A device for providing sustained, prolonged release of a chemoattractant to cells in a surrounding biological medium and for trapping cells attracted by said chemoattractant, said device comprising:
- (a) a biocompatible non-inflammatory body comprising said chemoattractant sequestered therein, said body providing sustained prolonged release of said chemoattractant from at least a portion thereof, and
- (b) a cell trap comprising a non-inflammatory wettable material attached to said body, chemoattractant released from said body being transmitted through said trap, and cells attracted by said chemoattractant released from said body being trapped by and retained within said trap.
Dependencies are inferred from the claim text.