(5,6-dichloro-3-oxo-2,3,9,9a-tetrahydrofluoren-7-yl)-alkanoic acids and alkanimidamides bearing novel functional 9a-substituents

A compound of the formula:

• ##STR18## wherein:
• R is --COOR.sup.1, ##STR19## R.sup.1 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 carboxyalkyl;
• R.sup.2 is NH.sub.2, NHR.sup.4 or NR.sup.4 R.sup.5 ;
• R.sup.3 is NH or NR.sup.4 ;
• R.sup.4, R.sup.5 are each independently lower alkyl, branched or unbranched, containing from 1 to 5 carbon atoms, or amino, provided that R.sup.4 and R.sup.5 are not both amino;
• wherein R.sup.2 and R.sup.3 may be joined together via R.sup.4 to form a heterocyclic ring of 5 or 6 atoms containing 2 nitrogen atoms and 3 or 4 carbon atoms, ##STR20## or wherein R.sup.4 or R.sup.5 may be joined together to form a 5- or 6-membered ring containing one nitrogen atom and 4 or 5 carbon atoms, ##STR21## R' is C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.1 -C.sub.6 haloalkyl, C.sub.1 -C.sub.6 acyloxyalkyl, and C.sub.1 -C.sub.6 alkoxyalkyl;
• X and Y are halo or lower alkyl;
• and
• x is 1 to 4, or the pharmaceutically acceptable salts thereof.