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US 4,731,459 AGranted
Novel anti-ulcer agents and quassinoids
AssigneeShionogi & Co., Ltd.
InventorsHaruhiko Tada, Masami Doteuchi, Fumio Yasuda, Koichi Otani
Life of this patent
Estimating the term…
Abstract
Highly effective anti-ulcer agents, i.e. Quassinoids of the following formula: ##STR1## wherein R is hydrogen or hydroxy; X is >C.dbd.CH.sub.2, >CH--CH.sub.3, or ##STR2## and the 3,4-dotted line indicates the presence or absence of a double bond.
Claims2
A compound of the following formula:
- ##STR7## wherein R is hydrogen or hydroxy;
- Y is >CH--CH.sub.3 or ##STR8## and the 3,4-dotted line indicates the presence or absence of a double bond provided that the case wherein R is hydrogen, Y is .dbd.CH--CH.sub.3, and the dotted line indicates the presence of a double bond is excluded.
An anti-ulcer composition which comprises an anti-ulcer effective amount of a compound of the formula ##STR9## wherein R is hydrogen or hydroxy;
- Y is >CH--CH.sub.3 or ##STR10## and the 3,4-dotted line indicates the presence or absence of a double bond provided that the case wherein R is hydrogen, Y is .dbd.CH--CH.sub.3, and the dotted line indicates the presence of a double bond is excluded,
- and a pharmaceutically acceptable carrier therefor.
Dependencies are inferred from the claim text.