Coumarin derivatives and antiallergic agents containing the same
AssigneeKaken Pharmaceutical Co., Ltd.
InventorsJun Nakano, Toshikazu Awaji, Kiyoshi Kuriyama, Yoshiyuki Hiyama, Toshiaki Okuda
Life of this patent
Estimating the term…
Loading patent…
AssigneeKaken Pharmaceutical Co., Ltd.
InventorsJun Nakano, Toshikazu Awaji, Kiyoshi Kuriyama, Yoshiyuki Hiyama, Toshiaki Okuda
Estimating the term…
A chromene derivative having the general formula (I): ##STR1## wherein n is 1 to 5 and --O--CH.sub.2).sub.n CO.sub.2 H group is attached to 5-position, 6-position, 7-position or 8-position, or salts thereof, a process for preparing the same and antiallergic agents containing the same. The compounds of the present invention inhibit the immunological release of chemical mediators such as SRS-A and histamine from mast cell and have an excellent effect in preventing and treating the various allergic diseases such as allergic asthma, allergic dermatitis, allergic nasitis, hives, allergic enteritis and allergic conjunctivitis, especially allergic asthma.
A chromene derivative having the general formula (I):
A pharmaceutical composition which comprises:
Dependencies are inferred from the claim text.