Cell for electrically controlled transdermal drug delivery
AssigneeIonics, Incorporated
InventorEdgardo J. Parsi
Life of this patent
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Abstract
A cell for electrically controlled drug delivery into and through the skin consisting of a source of current, an electrode, and a drug reservoir in which a drug is bound by an ion exchange medium or an immobilized ligand affinity medium. An additional ion reservoir may be interposed between the electrode and the drug reservoir and semi-permeable membranes are employed as barriers between the various components of the device as required.
Claims9
A cell for the electrically controlled delivery of a drug into and through the skin of a subject patient comprising in combination:
- a. a drug reservoir containing therein a drug bound to an immobilized ligand affinity medium or an ion-exchange medium;
- b. an electrode communicating with said reservoir;
- and
- c. a source of current connected between said electrode and said skin.
A cell for use in the electrically controlled delivery of a drug into the skin of a subject patient comprising in combination:
- a. a drug reservoir containing therein a drug bound to an immobilized ligand affinity medium or an ion-exchange medium;
- b. a first semi-permeable barrier interposed between said drug reservoir and said skin;
- c. an ion reservoir positioned adjacent to said drug reservoir;
- d. a second semi-permeable barrier interposed between said drug reservoir and said ion reservoir;
- e. an electrode communicating with said ion reservoir;
- and
- f. a source of current connected between said electrode and said skin.
Dependencies are inferred from the claim text.