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US 4,730,053 AGranted
S-[2-phenyl (alkyl) carbamoyl]-phenylselenylmercapto derivatives
AssigneeA. Nattermann & Cie GmbH
InventorsNorbert Dereu, Albrecht Wendel, Helmut Sies, Sigurd Leyck, Axel Romer, Erich Graf
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Abstract
The present invention is related to new S-(Carbamoyl-phenylselenyl) derivatives of mercaptanes of the general formula (I) ##STR1## and to a process for the treatment of diseases caused by cell injury due to the increased formation of active oxygen metabolites.
Claims4
A compound of formula (I) ##STR7## wherein R.sup.1, R.sup.2,
- R.sup.3 and R.sup.4 are identical or different from each other and represent members selected from the group consisting of hydrogen, halogen, C.sub.1-4 -alkyl, C.sub.1-3 -alkoxy, trifluoromethyl, nitro, cyano, hydroxy, carboxy, C.sub.1-2 -alkoxycarbonyl, carboxy-C.sub.1-4 -alkyl and C.sub.1-2 -alkoxycarbonyl-C.sub.1-4 -alkyl and
- A represents a member selected from the group constisting of the straight and branched alkyl groups having 1 to 4 carbon atoms and said alkyl groups substituted by 1 to 3 members selected from the group consisting of the carboxy, C.sub.1-3 -alkoxycarbonyl, hydroxy, mercapto, carboxy-C.sub.1-4 -alkylcarbamoyl, C.sub.1-3 -alkoxycarbonyl C.sub.1-4 -alkylcarbamoyl, phenyl, carboxyphenyl, C.sub.1-3 -alkoxycarbonylphenyl, pyridyl and pyridyl-C.sub.1-4 -alkyl groups, and
- n is zero or one.
Dependencies are inferred from the claim text.